Table 1. Effect of treatment with canagliflozin (C) on some physiological parameters in rats with adenine (A)-induced chronic kidney disease (CKD). Values in the table are means SEM (n = 6). CKD was induced by the inclusion of A in the feed at a concentration of 0.25%w/w for 35 days, and C was given to rats concurrently by oral gavage. On the 35th day of treatment, the rats were placed in metabolic cages to collect urine. Different superscripts indicate significance as follows (P < 0.05 was considered significant): a Control vs all groups. b A vs adenine treated groups