Table 3. Effect of treatment with canagliflozin (C) on some urinary constituents in rats with adenine (A)-induced chronic kidney disease (CKD). Values in the table are means SEM (n = 6). CKD was induced by the inclusion of A in the feed at a concentration of 0.25%w/w for 35 days, and C was given to rats concurrently by oral gavage. On the 35th day of treatment, the rats were placed in metabolic cages to collect urine. NAG: N-acetyl-β-glucosaminidase; L-FABP: Liver-type fatty acid binding protein; 8-OHDG: 8-hydroxy-2'-deoxyguanosine. Different superscripts indicate significance as follows (P < 0.05 was considered significant): a Control vs all groups.b A vs adenine treated groups