Fig. 10. The p38-Wip1 loop in normal and PE placentas. A. Western blotting of p38-Wip1 loop consisting molecules in Normal and PE complicated human placentas, Welch's t-test for p-p53/p53 and student's-t test for others, n=7. β-actin was used as loading control, *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001. Experiments were performed in triplicate; B. Working model of the p38-Wip1 feedback loop in trophoblasts.