Fig. 5. Inhibition of Mdm2 degradation down-regulates p38-Wip1 loop. Representative Western blotting of p38-Wip1 loop consisting molecules in HTR8/SVneo cells after 24 h of HII or SIB in the presence of 6 ÁM MG-132, Kruskal-Wallis test, Dunn's multiple comparison test for p-p53/p53 and one-way ANOVA, Dunnett-t multiple comparison test for others. n=4, β-actin was used as loading control. *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001. Experiments were performed in triplicate.