Fig. 5. miR-186-5p targets FOXK1 3'-UTR directly. (A,B) Relative luciferase activity was detected by fluorescent intensity. Wt: wild-type FOXK1 3′-UTR transfection; Mut: mutated-type FOXK1 3′-UTR transfection. (C) Spearman's rank correlation analysis of the expression levels between miR-186-5p and FOXK1 protein in OS tissues. Values presented as mean SD. *P<0.001, v.s. control.