Fig. 3. Effects of HUVEC/RPE cells co-culture on mitochondrial membrane potential in RPE cells, in physiological (A and C) and peroxidative (B and D) conditions. In A and B, the effects of Aflibercept, and in C and D, the effects of Ranibizumab, are shown. Abbreviations are as in previous Fig.s. The data were normalized versus control value. Reported data are means SD of five independent experiments for each experimental protocol. Significance between groups: *P<0.05 vs C; #P<0.05 vs 200 μM H2O2. Short square brackets indicate significance between groups (P<0.05).