The current and former Publishers and Editor are jointly issuing an Expression of Concern on the article entitled

“Effects of PKM2 Gene Silencing on the Proliferation and Apoptosis of Colorectal Cancer LS-147T and SW620 Cells”
[Cell Physiol Biochem 2017;42:1769–1778; DOI: 10.1159/000479456]
by Ran Ao, Lin Guan, Ying Wang and Jia-Ni Wang.

After publication of this article, concerns were raised about the integrity of some of the data presented in the article. The authors were unresponsive to our correspondence within the given timeframe. The matter was raised to the corresponding author's institution who confirmed the launch of an internal investigation into the concerns. Until the conclusion of this investigation, readers should interpret the data presented in the article with caution. Appropriate editorial action will be taken once the investigation is concluded.