Special Issue 2 (in Progress)
Molecular Mechanisms of Cancer Pathogenesis
Cancer is a disease of the genome, arising from DNA alterations that dysregulate coding and non-coding genes. Unraveling the cancer pathogenesis and the complex interconnected signaling pathways have important implication on identification of new therapeutic targets and the development of novel biomarkers for diagnostic and/or prognostic. In this Special Issue, we intend to highlight key molecular mechanisms required for malignancy, emphasis the interconnection among the oncogenic signaling, leading to the identification of key ‘cancer genes’ that affect those pathways, being a starting point for new targeted therapies.
Assoc. Prof. Cornelia Braicu & Prof. Ioana Berindan-Neagoe (Editors)
Typical Lung Carcinoids with Metastasis: Potential Role of MicroRNAs in the Regulation of Adaptive Immunity Associated with Disease: a Case Study
Seneda A., Lapa R., Felix T., Minutentag I., Campos C., Oliveira R., Oliveira C., Hasimoto É., Cataneo D., Cataneo A., De Faveri J., Drigo S., Mur L., Reis P.
Cell Physiol Biochem 2021;55(S2):1-12
Pathological and Prognostic Indications of the mdig Gene in Human Lung Cancer
Shi J., Thakur C., Zhao Y., Li Y., Nie L., Zhang Q., Bi Z., Fu Y., Wadgaonkar P., Almutairy B., Xu L., Zhang W., Qiu Y., Rice M., Cui H., Chen F.
Cell Physiol Biochem 2021;55(S2):13-28