Special Issue - Molecular Mechanisms of Cancer Pathogenesis
Cancer is a disease of the genome, arising from DNA alterations that dysregulate coding and non-coding genes. Unraveling the cancer pathogenesis and the complex interconnected signaling pathways have important implication on identification of new therapeutic targets and the development of novel biomarkers for diagnostic and/or prognostic. In this Special Issue, we intend to highlight key molecular mechanisms required for malignancy, emphasis the interconnection among the oncogenic signaling, leading to the identification of key ‘cancer genes’ that affect those pathways, being a starting point for new targeted therapies.
Guest Editor:
Assoc. Prof. Cornelia Braicu & Prof. Ioana Berindan-Neagoe
Iuliu Haţieganu, University of Medicine and Pharmacy, Cluj-Napoca, Romania
Typical Lung Carcinoids with Metastasis: Potential Role of MicroRNAs in the Regulation of Adaptive Immunity Associated with Disease: a Case Study
Seneda A., Lapa R., Felix T., Minutentag I., Campos C., Oliveira R., Oliveira C., Hasimoto É., Cataneo D., Cataneo A., De Faveri J., Drigo S., Mur L., Reis P.
Cell Physiol Biochem 2021;55(S2):1-12
Pathological and Prognostic Indications of the mdig Gene in Human Lung Cancer
Shi J., Thakur C., Zhao Y., Li Y., Nie L., Zhang Q., Bi Z., Fu Y., Wadgaonkar P., Almutairy B., Xu L., Zhang W., Qiu Y., Rice M., Cui H., Chen F.
Cell Physiol Biochem 2021;55(S2):13-28
Prognosis of Different Types of Non-Small Cell Lung Cancer Progression: Current State and Perspectives
Schegoleva A., Khozyainova A., Fedorov A., Gerashchenko T., Rodionov E., Topolnitsky E., Shefer N., Pankova O., Durova A., Zavyalova M., Perelmuter V., Denisov E.
Cell Physiol Biochem 2021;55(S2):29-48
Proteome Linked Biochemical Targets: Can Repair Defective Cellular Physiological Mechanisms?
Dubey A., Prasad A., Poluri K., Kumar A., Kumar A., Mishra A.
Cell Physiol Biochem 2021;55(S2):49-70
The Influence of Psychological Stress on HPV Infection Manifestations and Carcinogenesis
Lugović-Mihić L., Cvitanović H., Djaković I., Kuna M., Šešerko A.
Cell Physiol Biochem 2021;55(S2):71-88
Oh, the Mutations You’ll Acquire! A Systematic Overview of Cutaneous Squamous Cell Carcinoma
Droll S., Bao X.
Cell Physiol Biochem 2021;55(S2):89-119
Proteasome Based Molecular Strategies Against Improper Cellular Proliferation
Dubey A., Kinger S., Jagtap Y., Patwa S., Kumar P., Singh S., Kumar A., Kumar A., Mishra A.
Cell Physiol Biochem 2021;55(S2):120-143
Cholesterol Triggers Nuclear Co-Association of Androgen Receptor, p160 Steroid Coactivators, and p300/CBP-Associated Factor Leading to Androgenic Axis Transactivation in Castration-Resistant Prostate Cancer
Pimenta R., Camargo J., Candido P., Ghazarian V., Gonçalves G., Guimarães V., Romão P., Chiovatto C., Mioshi C., dos Santos G., Silva I., Birbrair A., Srougi M., Nahas W., Leite K., Viana N., Reis S.
Cell Physiol Biochem 2022;56(S4):1-15